ABSTRACT
Background: Since December 2019 an unprecedented coronavirus pandemic (COVID-19) in Italy and in all the world, has been spreading. This study is a retrospective overview of Italian population in one year of COVID-19. This study aimed to assess the changes of COVID-19 distribution during the first, second and third waves throughout Italy. Subjects dan Method: This was a retrospective study carried out in all Italian regions from symptomatic or COVID-19 high-risk exposure patients. 41,135,655 nasopharyngeal swabs samples were obtained and analyzed between man and woman in five age categories. The dependent variables were positivity rate and collection period. The independent variables were age and gender. The swabs were processed by qRT-PCR technique. The data were extrapolated by QLink software and evaluated using chi-square test statistical analysis.